Difference between Norelgestromine-Ethinyl Estradiol 150-35 and 150-20
When it comes to hormonal contraceptives, Norelgestromine-Ethinyl Estradiol (EE) is a well-known option. This medication combines the progestin norelgestromine with the estrogen ethinyl estradiol to prevent pregnancy. In this article, we will delve into the differences between two specific formulations: Norelgestromine-Ethinyl Estradiol 150-35 and 150-20. By understanding these differences, you can make an informed decision about which option is best for you.
Understanding the Basics
Norelgestromine-Ethinyl Estradiol is a combined oral contraceptive pill (COCP) that works by inhibiting the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which are necessary for ovulation. The progestin norelgestromine also thickens the cervical mucus, making it more difficult for sperm to reach the egg. Ethinyl estradiol, on the other hand, helps to maintain the lining of the uterus and prevent the implantation of a fertilized egg.
Formulation Differences
The primary difference between Norelgestromine-Ethinyl Estradiol 150-35 and 150-20 lies in the dosage of the hormones. The “150” in the name refers to the amount of norelgestromine in the pill, while the “35” and “20” represent the amount of ethinyl estradiol. Let’s take a closer look at the specific dosages:
| Component | Norelgestromine-Ethinyl Estradiol 150-35 | Norelgestromine-Ethinyl Estradiol 150-20 |
|---|---|---|
| Norelgestromine | 150 mcg | 150 mcg |
| Ethinyl Estradiol | 35 mcg | 20 mcg |
As you can see, the dosage of norelgestromine remains the same in both formulations, while the ethinyl estradiol dosage is lower in the 150-20 version.
Effects on Menstrual Bleeding
One of the most common reasons women choose hormonal contraceptives is to regulate their menstrual bleeding. The lower ethinyl estradiol dosage in the 150-20 formulation may result in lighter menstrual bleeding compared to the 150-35 version. However, it’s important to note that individual experiences may vary, and some women may still experience heavy bleeding or spotting.
Side Effects
Both Norelgestromine-Ethinyl Estradiol 150-35 and 150-20 can cause side effects, although not everyone will experience them. Common side effects include nausea, breast tenderness, mood changes, and breakthrough bleeding. It’s essential to discuss any concerns with your healthcare provider, as they can help you manage these side effects or suggest alternative options if necessary.
Effectiveness and Contraindications
Both formulations are highly effective at preventing pregnancy when used correctly. However, it’s important to note that Norelgestromine-Ethinyl Estradiol is not suitable for everyone. Contraindications include a history of blood clots, certain types of cancer, liver disease, and uncontrolled high blood pressure. Always consult with your healthcare provider before starting any new medication.
Conclusion
In summary, the main difference between Norelgestromine-Ethinyl Estradiol 150-35 and 150-20 is the dosage of ethinyl estradiol. The 150-20 formulation may result in lighter menstrual bleeding, but individual experiences may vary. Both formulations are highly effective at preventing pregnancy, but they are not suitable for everyone. Always consult with your healthcare provider to determine the best option for you.
